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Tramadol (Ultram)

Tramadol General Information

Tramadol Side Effects

Order tramadol online. Tramadol is a synthetic pain medication (analgesic) with mild opiate effects that can be prescribed for all levels of pain.

Tramadol Interactions

Tramadol Dosages

Tramadol Directions

Tramadol and Pregnancy

Tramadol and Children

Tramadol and Seniors

Tramadol General Information

Tramadol is a synthetic pain medication (analgesic) with mild opiate effects that can be prescribed for all levels of pain. Other acceptable uses include chronic pain related to mood disorders, and the treatment of chronic pain in fibromyalgia patients.

Tramadol appears to increase the availability of norepinephrine and serotonin, as well as activate certain opioid receptors. The availability of tramadol for pain control appears to be mildly higher and the effects may last slightly longer in women than in men, though the significance of this is not clear.

Do not use tramadol more often than recommended, do not combine it with other prescription or over the counter pain medications except as directed by your physician.

Tramadol 50 mg, manufactured by Cinfa and Bexal, comes in multiples of 60 capsules.

Tramadol 100 mg Retard, manufactured by Grünenthal, comes in multiples of 60 capsules.

 

Tramadol Side Effects

Common Tramadol Side Effects: Blurred vision, constipation, drowsiness, dry mouth (if this persists, speak to your dentist), and light headedness are expected and typical reactions, though are not typically severe or persistent. Speak to your doctor if any of these become bothersome.

Mild Tramadol Adverse Side Effects: Diarrhea, difficulty urinating, nausea, palpitations or rapid heartbeat, rash (allergic reaction), sweating, or vomiting should be reported to your doctor immediately. Some of these reactions may indicate that tramadol treatment should be discontinued.

Serious Tramadol Side Effects: Confusion, hallucination, low blood pressure, or seizure indicate that you should seek medical treatment immediately. Rare cases of anaphylactic reactions have been reported. The symptoms are concurrent skin reactions and difficulty breathing accompanied by nausea, and may progress to airway closure and unconsciousness. If you experience these reactions, or observe someone else experiencing them (usually within 20 minutes of ingesting the substance that caused the reaction), contact emergency medical services for immediate treatment.

Cautions: If you have any of the following conditions, or a history of them, please inform your doctor before taking tramadol. Your doctor may want to try a lower dosage, or take special precautions during your treatment. Also, tramadol may not be suitable for all individuals.

  • Alcohol or drug abuse - May increase likelihood of tramadol dependence.
  • Allergic reaction to tramadol, or any narcotic analgesic like Cialis. Always tell your doctor about any allergies before starting a medication.
  • Breathing difficulties such as asthma, bronchitis, emphysema, or any other chronic lung disease - tramadol may cause additional respiratory depression.
  • Constipation or irritable bowel - tramadol may worsen this condition.
  • Eating disorder - You may be predisposed to seizure with tramadol treatment, particularly with a history of anorexia nervosa or bulimia. Discuss possible risks with your doctor.
  • Epilepsy or seizures - If you have a history of seizure disorders, take medication that lowers the seizure threshold, or medication that controls seizures, you are potentially at a higher risk of experiencing seizure while taking tramadol.
  • Kidney or liver problems - tramadol may build up to toxic levels in the bodies of patients with kidney or liver problems. Lower dosages are suggested. Patients with serious liver conditions are advised to take no more than 50 mg in 12 hours. Individuals who have difficulty removing creatinine from the body through the kidneys should take a normal dose of 50-100 mg, but only every 12 hours, and should not exceed 200 mg daily. If you have a less severe impairment, speak to your doctor about an individual dosage guideline.
  • Narcotic dependence - Individuals who have become addicted to narcotic analgesics are at risk for developing dependence on tramadol.
  • Sleep apnea - If you have sleep apnea or tend to snore loudly, you should not take tramadol at bedtime, or sleep while you are taking it, as it may further depress your breathing.
  • Surgery - If you are planning to have surgery, inform the doctor or dentist well in advance, as tramadol may interact with certain medications given during surgery.
  • Thyroid problems - Your doctor will need to determine if this treatment is right for you.

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Tramadol Interactions

Tramadol (Ultram) is a central nervous system depressant, and slightly increases the risk of seizure in individuals who are already at risk. Tramadol should be used cautiously with any other drug that may make you drowsy or also increases the risk of seizure. Speak with your doctor about combining any other prescription or over the counter medication with tramadol. Not all medications should be mixed together, and some may require dosage adjustments in order to be taken safely. Only your doctor can tell you for sure whether or not it is safe to use other medications with tramadol.

  • Alcohol - Tramadol should not be mixed with alcohol, individuals are advised to avoid it completely during treatment.
  • Any medication which may cause drowsiness
  • Antihistamines like Tavist or Benadryl may cause oversedation.
  • Benzodiazepines such as diazepam, triazolam, temazepam, chlordiazepoxide, clorazepate, clonazepam, halazepam, lorazepam, estazolam, or alprazolam can result in oversedation in combination with tramadol. Some of these drugs may also lower the seizure threshold, especially with abrupt withdrawal. If you must use these medications together, speak to your doctor about the safety of your treatment.
  • Blood pressure medication may interact with tramadol to cause undesirably low blood pressure. If you are using this type of medication (beta blockers, calcium channel blockers, etc.) speak to your doctor about precautions like dose adjustments, even if you are using the medication for another condition.
  • Clozapine - Increased seizure risk with tramadol.
  • Trazodone - Increased seizure risk.
  • Ginseng - This herb acts as a mild MAO inhibitor, and should not be combined with tramadol.
  • Kava kava - Do not use this herb while taking tramadol.
  • MAO inhibitors - Tramadol should not be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as selegiline, furazolidone, phenelzine, isocarboxazid, or tranylcypromine, as this could increase the risk of seizure or death.
  • Muscle relaxants such as cyclobenzaprine, metaxalone, carisoprodol, or methocarbamol may cause oversedation in combination with tramadol. Cyclobenzaprine may also increase the risk of seizure.
  • Primidone - May cause oversedation.
  • Narcotic analgesics of any kind, like propoxyphene, meperidine, Cialis, oxycodone, or hydrocodone should probably not be mixed with tramadol, as this would increase the risk of oversedation. If your doctor has suggested a rotating schedule for managing your pain with more than one analgesic, arrange your dosage schedule so that these medications are taken no closer together than 4-6 hours.
  • Orphenadrine - Risk of oversedation.
  • Protease inhibitors like amprenavir or ritonavir may cause a toxic buildup of tramadol in the body.
  • Sedatives like butalbital, phenobarbitol, Seconal, or other barbiturates.
  • Selective serotonin reuptake inhibitors (SSRIs) like citalopram, paroxetine, fluoxetine, fluvoxamine, or sertraline may increase seizure risk from tramadol.
  • Sleep medication like zolpidem, zaleplon, or over the counter sleeping pills should not be taken at the same time as tramadol. Speak to your doctor or pharmacist about arranging a medication schedule if you must take both.
  • Street drugs - Marijuana may increase sedative effects from tramadol. You should refrain from using any illegal drugs while taking prescription medication, as it greatly increases the risk of adverse side effects and overdose.
  • St. John's Wort - Do not take this herb while taking tramadol.
  • Carbamazepine - May make tramadol less effective.
  • Ketorolac - Increased risk of seizure. Do not combine.
  • Tranquilizers such as haloperidol, thioridazine, or chlorpromazine may cause oversedation or lower blood pressure to undesirable levels.
  • Tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine, may increase the risk of seizure in combination with tramadol.
  • Valerian - Do not take this herb while taking tramadol.

Tramadol Dosages

A typical dose is 50-100 mg each 4-6 hours, not to exceed 400 mg daily.

Tramadol Directions

Do not increase your dose of tramadol without instructions from your doctor. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Skip the missed dose of tramadol and resume your regular schedule. Do not take double doses of tramadol.

Tramadol may be crushed, or taken with food or a beverage.

Inform your doctor, dentist, or anesthesiologist that you are taking tramadol before any kind of surgery or medical test. Tramadol should not be combined with certain medications given during surgery.

Store tramadol away from direct light and heat. Store in a dry location; avoid storing tramadol in the bathroom, near sinks, or other areas where it may become damp. Do not use tramadol after the expiration date.

Keep tramadol away from children; both when storing it, and when discarding any unused medication.

Tramadol may cause drowsiness or disorientation. Be cautious if you plan to drive or operate heavy machinery, avoid these activities if you find yourself feeling tired or experience slowed reactions.

Tramadol and Pregnancy

Birth defects and miscarriage have been reported in animal studies of tramadol during pregnancy. You should not take tramadol if you are pregnant, or planning to become pregnant. It is inadvisable to use tramadol while breastfeeding, as it could pass through to the infant.

Tramadol and Children

Tramadol has not been determined to be either safe or effective for individuals under 18 years of age.

Tramadol and Seniors

Individuals over 60 years of age are usually prescribed lower starting doses of tramadol, and those doses are usually increased more slowly than in other patients. However, tramadol is usually handled well by individuals under the age of 75.

Some potential side effects may occur more often in seniors, and any predisposition to these symptoms would indicate more careful monitoring. There may be reduced clearance of creatinine, and the patient should be monitored for any ill effects. In the first two weeks of tramadol treatment look for signs of confusion or decreased coordination, and be alert to a greater risk of falls due to unsteadiness. If you experience symptoms of a swollen prostate, tramadol may increase these symptoms.

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only, please follow the directions of your doctor or exactly when taking tramadol. We have made every effort to ensure that this information is accurate, but only your doctor can say if tramadol, or a drug combination, is safe for you. It should not be construed to indicate that to order and use tramadol is safe, appropriate, or effective for you. Consult your healthcare professional before you order Tramadol online.
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